Partner Profile

The Saez Lab is interested in developing and applying computational methods to acquire a functional understanding of signaling networks and their deregulation in disease, and to apply this knowledge to develop novel therapeutics. Our current emphasis is on use of single-cell technologies (primarily scRNA and mass cytometry) and understanding multi-cellular communication. Towards this end we combine data with prior knowledge. Our applications span from cancer to fibrosis in the context of chronic kidney disease.