Lab Profile

Molecular Brain Development

We aim to understand how neurotransmitter signaling controls cortical development and evolution by studying different mammalian species, most importantly mice and humans. From a clinical point of view, neurotransmitter systems are a target of many drugs, thus providing the risk and potential to influence cortical development through environmental exposure in healthy and disease conditions, respectively.

We employ a large range of methodologies ranging from single-cell RNA-Sequencing to immunohistochemistry, live cell imaging, and mass spectrometry on cells and tissue samples from animal models and patient donations. In order to achieve this, we collaborate with experts in the fields of bioinformatics, biophysics, and biochemistry, as well as clinicians.

  • Brain development
  • scRNA-Seq
  • calcium imaging
  • multimodal analysis
  • stem cells

Institution Name

Hertie-Institute for Clinical Brain Research

Institution Short Name


Institution Address

Otfried-Müller-Strasse 27, 72076 Tübingen, Germany

Institution Website


Principal Investigator

Simone Mayer

Independent Research Group Leader

Otfried-Müller-Strasse 27,
72076 Tübingen, Germany

Tel.:+49 (0) 70712989191