Lab Profile


The brain relies on an enormous diversity of local interneurons to form specialized circuits with remarkable processing capacities. Yet how different interneuron types emerge during development and integrate into functional circuits remains unclear.

Using genetic fate mapping strategies combined with statistical and machine learning-based methods, our goal is to elucidate the intrinsic and extrinsic factors that drive cellular decision-making during interneuron development. We are using high-throughput single cell RNA-sequencing methods to reconstruct developmental trajectories and are building an integrated framework to understand how a cell’s spatial localization, epigenomic landscape, parental lineage and neural network activity influence its behavior and fate.

  • neuroscience
  • development
  • diversification
  • telencephalon
  • inhibition

Institution Name

Max Planck Institute of Neurobiology

Institution Short Name


Institution Address

Am Klopferspitz 18,
82152 Munich, Germany

Institution Website


Principal Investigator

Christian Mayer

Max Planck Research Group Leader

Max Planck Institute of Neurobiology
Department of Neurogenomics
Am Klopferspitz 18, 82152 Martinsried (Munich), Germany

Tel.:+49 (0) 9313181341