Lab Profile

Single-Cell Analysis

Pathogenic bacteria can reside in a mammalian host for a life-long period and chronic carriers form a reservoir leading to recurrent infections. Despite the importance of chronic infections for public health, how a subset of pathogens escape the host’s immune surveillance and how the host contains the spread of bacteria are still poorly understood. Scientists within the Single-Cell Analysis group develop and use single-cell transcriptomics and computational approaches to decipher the microenvironments of individual pathogens and ultimately their functional consequences on infection outcome.

  • Host-pathogen interactions
  • Salmonella
  • Drop-seq
  • Smart-seq
  • SLAM-seq

Institution Name

Helmholtz Institute for RNA-based infection research

Institution Short Name


Institution Address

Josef-Schneider-Str. 2/D15,
97080 Würzburg, Germany

Institution Website


Principal Investigator

Antoine-Emmanuel Saliba

Group Leader

Josef-Schneider-Str. 2/D15
97080 Würzburg Germany

Tel.:+49 (0) 9313181341