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Next Event

Date

Sep 15 2020
Expired!

Time

2:00 pm - 6:00 pm

Labels

SCOG event

Virtual SCOG workshop ‘Temporal Single Cell Analysis’

Hosts:
Fabian Theis, Institute of Computational Biology, Helmholtz Munich
Emmanuel Saliba, Helmholtz Institute for RNA-based infection research, Würzburg

A major obstacle to understanding dynamical processes in biology is that they happen in the scale of a few hours and are highly heterogeneous and asynchronous across cells. We are currently lacking a clear molecular, temporal and spatial picture of transition processes.

Recent advances in single-cell and computational technologies are making addressing these challenges possible. Thus, this workshop will bring together experts in temporal single-cell technologies from the experimental and computational sides that are developing novel methods to uncover cellular transitions. The sessions will cover the new exciting fields of RNA metabolic labeling and velocity.

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Hourly Schedule

Session I (14.00-16.10): Computational approaches

14.00 - 14.10
Welcome
Fabian Theis/Emmanuel Saliba
14.10 - 14.40
Caroline Uhler: Single-cell data integration: From observations to mechanisms
Department of Biosystems Science and Engineering, ETH Zürich, Switzerland
14.40 - 15.10
Gioele La Manno: Studying neural progenitor dynamics using RNA velocity
Laboratory of Neurodevelopmental Systems Biology, EPFL, Switzerland
15.10 - 15.40
Volker Bergen: RNA velocity: state-of-the-art & future directions
Institute of Computational Biology, Helmholtz Munich, Germany
15.40 - 16.10
Dana Pe’er: Trajectories and gene regulation
Sloan Kettering Institute, New York, USA
16.10 - 16.30
coffee break

Session II (16.30- 18.00): Labelling approaches

16.30 - 17.00
Florian Erhard: Infect me if you can - Studying virus infection in single cells
Computational Systems Biology and Bioinformatics, University of Würzburg, Germany
17.00 - 17.30
Alexander van Oudenaarden: From pseudo to real time: nascent transcripts & gastruloids
Hubrecht Institute Utrecht, Netherlands
17.30 - 18.00
Nikolaus Rajewsky: Topic: Cell cycle analysis with metabolic labeling
BIMSB/Max Delbrück Center Berlin, Germany
18.00 -
Closing remarks
Fabian Theis/Emmanuel Saliba