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SCOG Management Team
Email
contact.scog@gmail.com
Website
https://www.singlecell.de/
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Location

Virtual

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Next Event

Date

Nov 05 2021

Time

CEST
9:30 am - 10:15 am

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SCOG event

SCOG Virtual Lecture Series
‘Recent Advances in Single Cell Omics’:
30. Adrian Granada (Charité, Berlin)

We are excited to announce the next speaker in our SCOG Virtual Lecture Series ‘Recent Advances in Single Cell Omics’:  Adrian Granada (Charité, Berlin)
  • Title: ‘How proliferation cell cycle dynamics affect the responses of single cells to chemotherapy’
DNA damaging chemotherapeutics are widely used in cancer treatments, but they suffer from incomplete eradication of tumor cells and development of drug resistance. Recent studies have revealed how non-genetic cell-to-cell variability can drive significant phenotypic differences in response to identical drug treatment, leading to the hypothesis that the heterogeneity of cellular states might underlie the heterogeneous response within a tumor. In this talk I will present our recent study investigating how the dynamics of cellular states affect the response of individual cells to the chemotherapeutic drug Cisplatin. Our results show how two intertwined cellular states present in every cell have distinct control of cell fate choices in response to the chemotherapeutic drug Cisplatin. Contrary to tumor observations, we find that in dividing cells higher proliferation activity increases resistance and that cell cycle state determines the arrest likelihood of the surviving population. These findings show how the dynamics of cellular states shape the individual cell choices that collectively determine the overall response to therapy.

 

Further information on participation, the program and the application for a lecture can be found below.

VIRTUAL LECTURE SERIES: ‘Recent Advances in Single Cell Omics’
  • Biweekly event on Fridays at 9:30 am (CEST)
  • 30 min presentation, followed by 15 min discussion / Q&A
SYNOPSIS
The virtual lecture series includes biweekly presentations about current single cell research. In addition to selected presentations by invited guests, we would particularly like to offer SCOG partners a platform to present their work to the network (read below how to apply).
The program will be updated regularly (see schedule below).
PARTICIPATION
The Virtual Lecture Series takes place via Zoom. Please register in order to receive information on how to join the webinar. Your personal join link will be valid for all upcoming lectures of the series. REGISTER HERE.
Please note: We are changing the platform from GoToWebinar to Zoom! You have to register for the lecture series again, even if you have already registered before.  
APPLY FOR LECTURE
We would kindly like to encourage the SCOG community not only to participate as an attendee but to present their work to the community. All contributions are welcome.
If you are a SCOG partner (PI/group leader) or member (Postdoc) and would like to give a talk during the lecture series, please APPLY BY COMPLETING THIS FORM.
Please note that a balanced representation of topics, institutes and gender will be ensured in the selection of applications.

Hourly Schedule

Friday 15 January 2021

9:30am - 10:15am
Decoding host-pathogen interactions one cell at the time
Emmanuel Saliba (HZI/HIRI Würzburg)

Friday 29 January 2021

9:30am - 10:15am
Human organoid development through the lens of single-cell genomics
Barbara Treutlein (ETH Zurich)

Friday 26 February 2021

9:30am - 10:15am
Single cell computational epigenomics
Maria Colomé-Tatché (HMGU Munich)

Friday 12 March 2021

9:30am - 10:15am
Roles of Polycomb in Embryogenesis: Insights from single-cell transcriptomics
Stefanie Grosswendt (BIMSB/MDC Berlin)

Friday 26 March 2021

9:30am - 10:15am
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
Fabian Müller (USAAR Saarbrücken)

Friday 09 April 2021

4pm - 5:15pm
New single-cell technologies to dissect reprogramming and development
Samantha Morris (WUSTL, St. Louis, USA)

Friday 23 April 2021

9:30am - 10:15am
scRNA-seq reveals a macrophage subset that provides a splenic replication niche for intracellular Salmonella
Roi Avraham (Weizmann Institute of Science, Israel)

Friday 7 May 2021

9:30am - 10:15am
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro
Roser Vento-Tormo (Wellcome Sanger Institute, UK)

Friday 21 May 2021

9:30am - 10:15am
Investigating COVID-19 pathogenesis in hamster animal models
Emanuel Wyler (BIMSB/MDC, Berlin)

Friday 4 June 2021

9:30am - 10:15am
Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers
Herbert Schiller (HMGU, Munich)

Friday 2 July 2021

9:30am - 10:15am
Single-cell and spatial multi-omics mapping of blood and immune stem cells in health and disease
Simon Haas (BIH@Charité, BIMSB/MDC, Berlin)

Friday 16 July 2021

9:30am - 10:15am
Artificial Intelligence for Computational Hematopathology
Carsten Marr (HMGU, Munich)

Friday 10 September 2021

9:30am - 10:15am
Single cell epigenomics reveal zonation-specific differences in the ageing of liver and establish organoids as an ex vivo model system for ageing research
Peter Tessarz (MPI Age, Cologne)

Friday 24 September 2021

9:30am - 10:15am
tbd
Leif Ludwig (BIH@Charité, BIMSB/MDC, Berlin)

Friday 08 October 2021

9:30am - 10:15am
tbd
Heiko Lickert (HMGU, Munich)

Friday 22 October 2021

9:30am - 10:15am
tbd
Michela Deleidi (DZNE, Bonn)

Friday 05 November 2021

9:30am - 10:15am
How proliferation cell cycle dynamics affect the responses of single cells to chemotherapy
Adrian Granada (Charité, Berlin)