Single cell genomics is revolutionizing biology and medicine, combining the advantages of bulk sequencing techniques and microscopic analyses of single cells. Rapid technological advances now allow the profiling of genomes, transcriptomes and epigenomes at an unprecedented level of resolution. Computational methods tailored to the analysis of single cell -omics data are however lagging behind these technological advances. This limitation currently presents a major bottleneck and threatens to slow progress in the introduction of single cell sequencing techniques to the clinic. The SCGN is a network of researchers using single cell technologies and represents a collaborative platform for the exchange of both methods and experimental protocols for single cell -omics. Our network thus leverages the insights that single cell based technologies provide for biological systems to biomedical questions and translational research.